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purine nucleobases degradation II (anaerobic)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
4-aminoimidazole + H2O + H+ <=> NH3 + imidazolinone 3.5.4.8 aminoimidazolase

5-formimidoyltetrahydrofolate + glycine <=> Formiminoglycine + tetrahydrofolate 2.1.2.4 glycine formimidoyltransferase

xanthine + H2O <=> H+ + 5-ureido-4-imidazole_carboxylate 3.5.2

pyruvate + CoA + oxidized_ferredoxin <=> acetyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.1 pyruvate synthase
1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)



10-formyltetrahydrofolate + H2O <=> tetrahydrofolate + formate + H+ 3.5.1.10 formyltetrahydrofolate deformylase

5-amino-4-imidazole_carboxylate <=> 4-aminoimidazole + CO2 4.1.1

formate + NAD+ <=> CO2 + NADH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase


L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O 2.1.2.1 glycine hydroxymethyltransferase

ATP + acetate <=> ADP + acetyl_phosphate 2.1.2.2 phosphoribosylglycinamide formyltransferase
2.7.2.1 acetate kinase
2.7.2.15 propionate kinase
2.7.2.2 carbamate kinase




6,8-dihydroxypurine + H2O + NAD+ <=> Urate + NADH + H+ 1.17.1.4 xanthine dehydrogenase

purine + H2O + NAD+ <=> 8-hydroxypurine + NADH + H+ 1.17.1.4 xanthine dehydrogenase

5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)


phosphate + acetyl-CoA <=> acetyl_phosphate + CoA 2.3.1.19 phosphate butyryltransferase
2.3.1.222 phosphate propanoyltransferase
2.3.1.8 phosphate acetyltransferase



5-formimidoyltetrahydrofolate + H+ <=> NH3 + 5,10-methenyltetrahydrofolate 4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase

imidazolinone + H2O <=> Formiminoglycine 3.5.2

2-aminoacrylate <=> 2-iminopropanoate 4.3.1.17 L-serine ammonia-lyase
4.4.1.13 cysteine-S-conjugate beta-lyase
4.4.1.25 L-cysteate sulfo-lyase
4.4.1.28 L-cysteine desulfidase
4.4.1.35 L-cystine beta-lyase





H+ + H2O + guanine <=> NH3 + xanthine 3.5.4.3 guanine deaminase

5,10-methenyltetrahydrofolate + H2O <=> 10-formyltetrahydrofolate + H+ 3.5.4.9 methenyltetrahydrofolate cyclohydrolase

hypoxanthine + H2O + NAD+ <=> 6,8-dihydroxypurine + NADH + H+ 1.17.1.4 xanthine dehydrogenase

8-hydroxypurine + H2O + NAD+ <=> 6,8-dihydroxypurine + NADH + H+ not assigned

xanthine + NAD+ + H2O <=> Urate + NADH + H+ 1.17.1.4 xanthine dehydrogenase
1.17.3.2 xanthine oxidase


2-iminopropanoate + H2O <=> pyruvate + NH3 3.5.99.10 2-iminobutanoate/2-iminopropanoate deaminase
4.3.1.17 L-serine ammonia-lyase
4.4.1.13 cysteine-S-conjugate beta-lyase
4.4.1.25 L-cysteate sulfo-lyase
4.4.1.28 L-cysteine desulfidase
4.4.1.35 L-cystine beta-lyase






L-serine <=> 2-aminoacrylate + H2O 4.3.1.17 L-serine ammonia-lyase

5-ureido-4-imidazole_carboxylate + H2O + H+ <=> 5-amino-4-imidazole_carboxylate + CO2 + NH3 3.5.1
3.5.3


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